Gene therapy technique may help prevent cancer metastasis

Gene-regulating RNA molecules could help treat early-stage breast cancer tumors before they spread.

The spread of malignant cells around the body, hospital known as metastasis, is the leading cause of mortality in women with breast cancer.

Now, a new gene therapy technique being developed by researchers at MIT is showing promise as a way to prevent breast cancer tumors from metastasizing.

The treatment, described in a paper published today in the journal Nature Communications, uses microRNAs — small noncoding RNA molecules that regulate gene expression — to control metastasis.

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