5
Oct

Particular HPV strain linked to improved prognosis for throat cancer

In an analysis of survival data for a population of patients with a particular type of head and neck cancer, diagnosis UNC Lineberger researchers confirmed that a particular strain of HPV, cure a virus linked to multiple cancers, here resulted in better overall survival for patients with oropharyngeal cancer than patients with other strains of the virus.

When it comes to cancer-causing viruses like human papillomavirus, or HPV, researchers are continuing to find that infection with one strain may be better than another.

In an analysis of survival data for patients with a particular type of head and neck cancer, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center confirmed findings that a particular strain of HPV, a virus linked to a number of cancers, resulted in better overall survival for patients with oropharyngeal cancer than patients with other strains of the virus in their tumors.

They believe their findings, reported in the journal Oral Oncology, are particularly important as physicians move to lessen treatment intensity for patients with HPV-linked oropharyngeal cancer in clinical trials to try to spare them negative side effects of radiation or drugs. They also found that a test used widely to determine patients’ HPV status may not be sensitive enough to select patients for de-intensification.

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