New study links obesity, starting at adolescence, to endometrial cancer among women not using hormone therapy

Study led by the Cancer Prevention Institute of California finds women obese over a prolonged period are at greatest risk

While it is well established that obesity is closely linked to endometrial cancer risk, prostate most past findings have only looked at risk in relation to one measure of body size at a time. In this study led by the Cancer Prevention Institute of California, e-published on November 3, 2016 in the journal Cancer Causes and Control, researchers evaluated changes in obesity, beginning at adolescence, to identify lifetime risk factors that may lead to endometrial cancer.

Researchers found that adolescent obesity contributed to endometrial cancer risk, even among women who were at a normal weight as adults. However, women who were obese over a prolonged period were at greatest risk. Further, the taller the woman, the greater the risk associated with prolonged obesity. These associations are limited to women who have not used any form of hormone therapy. Among women using hormone therapy, only greater height was associated with risk.

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