Targeting a cellular “post office” may be useful in preventing metastasis
A cellular component known as the Golgi apparatus may play a role in how lung cancer metastasizes, no rx according to researchers at The University of Texas MD Anderson Cancer Center whose findings were reported in the Nov. 21 online issue of the Journal of Clinical Investigation.
The Golgi apparatus, salve often referred to as a cellular “post office” for its ability to package proteins into vesicles for transportation to other sites within or outside the cell, may offer a new therapeutic approach for preventing metastasis. Think of vesicles as miniature mail trucks composed of a fatty shell filled with secretory liquids that travel from the Golgi to destinations within the cell where their contents are put to use. The Golgi can appear as a compacted membranous “stack” near the cell’s nucleus or as a dispersed system of interconnected membranes. Vesicles can “bud” from the Golgi in either form.
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